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Solutions for Behavioural Research
Pharmacology & Neuroscience
Overview
What do you need to do?
| Observation | Product | |
|---|---|---|
| Score & analyse behaviours live or from video | The Observer XT | |
| Measure ultrasonic vocalisations | UltraVox XT | |
| Automatically monitor home cage behaviour of rodents | PhenoTyper | |
| Track movement and location of animals within an arena | EthoVision XT | |
| Assess the gait and footfalls of rodent models of diseases | CatWalk XT | |
| Examine memory, anxiety, activity etc in various paradigms | Mazes |
Recommended Products
EthoVision XT
EthoVision XT is the most widely published and comprehensive video tracking package, being highly flexible for use with virtually any organism, in any arena. Features include machine-learning, marker-less tracking of groups, automatic experimental control, and the most powerful data selection, display and analysis features on the market.
CatWalk XT
A complete system for automated quantitative gait analysis in rodents. Objectively and rapidly measure a range of gait and individual paw parameters.
DanioVision
The DanioVision system provides the perfect environment for zebrafish embryo and larvae testing.
UltraVox XT
Easy and affordable system.
Full-spectrum sound capture with one microphone.
Easy integration with other behavioral data.
Real-time waveform and spectrogram
Automatic call detection
Easy definition and labeling of calls
Compact setup
The Observer XT
A complete system to collect, analyse and present observational data, be it human or animal, live or from video. User-friendly, flexible, with the ability to integrate and analyse other data streams, The Observer XT is the perfect hub for many researchers across a variety of disciplines, such as: psychology; zoology; pharmacology; education and training.
Coy MCS
The Mechanical Conflict-Avoidance System – Harte, Morrow Method provides an operant method of pain testing in rodents.
Artinis Brite MKII
A wearable multi-channel fNIRS device for use in: brain oxygenation monitoring; sports science; functional studies; cerebral studies; and hyperscanning. Non-invasive and wireless, great for studies in and out of the lab.
Example Scenarios
Here are some of the scenarios relevant to Pharmacology & Neuroscience and the products that would be appropriate.
| Scenario | Recommended Products | |
|---|---|---|
| Social behaviour in group-housed animals | ||
| Maternal separation studies and monitoring calling behaviour in rat pups | ||
| Behavioural patterns in group-housed animals and hormone-behaviour interactions | ||
| Home cage testing, activity monitoring and circadian studies in rodents | ||
| Avoiding problems with coat colour variation (e.g. transgenics), sequences of animals with different coat colours and urine reflections | ||
| High-throughput screening (e.g. trials with 100+ zebrafish) | ||
| Passive avoidance and place preference tests | ||
| Resident-intruder and social interaction | ||
| Automation of the forced-swim test | ||
| Analysing pre-clinical drug effects |
Case Studies
Automated home cage observations as a tool to measure the effects of wheel running on cage floor locomotion De Visser L, Van den Bos R and Spruijt B.M.
The paper introduces PhenoLab as a tool to measure the effects of wheel running on the time distribution and daily organization of cage floor locomotor activity in mice. To study these effects, female C57BL/6 mice were assigned to either a running wheel group or a control group with no running wheel. Observations of home cage behavior and running wheel activity were continuously recorded during bo...
Behavioural analysis of transgenic mice overexpressing corticotropin-releasing hormone using The Observer and EthoVision. Dirks A, Groenink L, Verdouw M, van der Gugten J and Olivier B
Corticotropin-releasing hormone (CRH) plays a pivotal role in the response of an organism to various stressors. Furthermore, chronic elevated levels of CRH are implicated in human stress-related and affective disorders, including major depression. To gain more insight into the relationship between hyperactivity of the CRH system and associated neuroendocrine, autonomic, physiological and behavioral...Using UltraVox to measure rat pup ultrasound vocalizations as an anxiolytic or anxiogenic evaluation procedure. McNee M, Gleason D and McArthur R
Maternal separation of rat pups is an ethopharmacologically validated model of anxiety and is measured by the duration and frequency of ultrasound vocalizations (USVs) made by the pups during this separation. These cries occur between 35 and 45 kHz, and have been described as "distress vocalizations" or "isolation calls".In this article we describe the use of UltraVox in order t...