PhenoTyper

Pt2

Overview

The PhenoTyper is an observation home-cage system completely optimised for video tracking, where rodent behaviour is automatically monitored.  Activity and movement are continuously measured and analysed using EthoVision XT.  PhenoTyper can be configured to suit the behavioural test required. Using EthoVision XT 18 you can track two socially-housed rodents without adding a colour mark.

How it Works

  • Design the PhenoTyper home cage to suit your research (add running wheel and food and water dispensers).
  • Track two socially-housed rodents without using a colour mark. Gain valuable information on interactions e.g. nose-tail, nose-nose and side-by-side.
  • Design experiment(s) to include manually scored behaviours (e.g. feeding) and independent variables (e.g. animal code, strain, treatment) for automatic data selection
  • Define zones, such as ‘feeder’ or ‘shelter’, irrespective of whether the animal is in view
  • Activate light and sound stimuli to elicit additional behavioural responses, for example a sound stimulus is generated when a mouse approaches the shelter (used in anxiety-related behaviour and learning behaviour research)
  • Visualise your data and export tracks for presentations
  • Automatically analyse your data; time and distance related parameters can be calculated for independent variables and zones, such as: distance moved, time spent in shelter, activity patterns, distance from wall, number of stops and activity levels
  • The analysis of each parameter can be restricted to specific time intervals, behaviours or zones (e.g. compare patterns displayed during the day with those displayed during the night)


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Features and Benefits

Feature Benefit
Infra-red (IR) lights and an IR camera ensure reliable monitoring, regardless of ambient light conditions in the labMonitor animals during multiple circadian cycles
Top unit contains aversive white spot light Create a light-dark gradient for approach-avoidance behaviour testing
Top unit provides a yellow house light and single tone sound stimuli Conduct operant conditioning-tests
A wide range of add-ons availableFlexible configuration depending on the desired behavioural test
No need to move rodentStress-free environment for use in longer term studies
Track two socially-houses rodents without adding a colour markNo 'swaps' in tracking, and a host of additional parameters including nose-tail, nose-nose and side-by-side

Options

These are the options available for this product:

Option Purpose
EthoVision XTVideo tracking
LickometerMonitors frequency and duration of drinking
Mouse Feeding Monitor Monitors frequency and duration of food hopper visits, via IR beam breaks
Pellet DispenserProvides rewards in operant tasks
Activity WheelScores number of revolutions on running wheel
Optogenetics Add-onEnabling optogenetic experiments
Cognition WallDiscrimination learning

Scenarios

Here are some of the many scenarios which have used PhenoTyper:

Pharmacologists/Neuroscientists
Behavioural phenotyping of mutant mouse strains
Neuroscientists
Monitoring of circadian behaviour in mice
Behavioural pharmacologists
Assessing rodent's locomotor activity, exploratory behaviour, vertical behaviour, high throughput screening (up to 16 cages), circadian studies, environment enrichment and home cage testing

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